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The Most Shocking Grey's Anatomy Moments Of All Time

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    Photo: Courtesy of ABC.

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    Grey's Anatomy isn't all cute doctors and elevator hookups. Shonda Rhimes' long-running medical drama is also packed with shocking twists. Just when you think there's no hope for a patient, a more hopeful song from Snow Patrol comes on, and you know the guy's going to pull through. And just when you think a couple is done for, a surreptitious romantic moment brings them back together. And when it seems everything is going great at Seattle Grace, (a.k.a. Mercy West or Grey-Sloan Memorial), a bus or plane or ferry crash throws everything into chaos. Or, patients walk in dying of the actual plague.

    The most surprising Grey's moments are often sad, sometimes ridiculous, but always unexpected. Here are some of the most gasp-inducing moments from the past 13 seasons (yes, 13!). They're still every bit as dramatic, even when you know what's coming.

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    0 of 16

    When Jo Tells Alex She's Married
    Season 13, Episode 9 (2016)

    Jo withheld the fact that she was married from Alex because she was afraid he'd try to attack her husband. The scene is shocking enough on its own, but the conversation also leads Alex to consider taking a plea deal and go to jail, eliminating the need for Jo to testify. (Jo is worried that if she names her abusive ex on the witness stand in Alex's trial, he'll track her down and possibly hurt her.)

    That's definitely one way to end on a mid-season cliffhanger.

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    1 of 16

    When Jackson Stops April's Wedding
    Season 10, Episode 12 (2013)

    Possibly the most shocking thing about this moment was the fact that it took ten seasons for Grey's to get an interrupted wedding. Jackson gets a lot of points for this romantic gesture, but also a bunch of demerits for using this moment not just to really ruin things for April's would-be husband, but for Jackson's actual wedding date, too.

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    2 of 16

    When Cristina Almost Kills Alex
    Season 8, Episode 12 (2011)

    Sometimes the Grey's docs are more of a danger to each other than their patients. This isn't even the first time a doctor has gotten injured in the OR (see Derek's ex kind of stabbing him in the hand).

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    3 of 16

    The Explosion
    Season 2, Episode 17 (2006)

    Seriously, Meredith, I understand curiosity and everything, but maybe don't go out to watch the active explosive be taken away?

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    When Derek Dies
    Season 11, Episode 21 (2015)

    Did anyone really think they'd kill off McDreamy? Send him on a long fellowship to get Patrick Dempsey off the set? Sure. But hadn't Meredith been through enough?