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The Most Shocking Grey's Anatomy Moments Of All Time

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    Grey's Anatomy isn't all cute doctors and elevator hookups. Shonda Rhimes' long-running medical drama is also packed with shocking twists. Just when you think there's no hope for a patient, a more hopeful song from Snow Patrol comes on, and you know the guy's going to pull through. And just when you think a couple is done for, a surreptitious romantic moment brings them back together. And when it seems everything is going great at Seattle Grace, (a.k.a. Mercy West or Grey-Sloan Memorial), a bus or plane or ferry crash throws everything into chaos. Or, patients walk in dying of the actual plague.

    The most surprising Grey's moments are often sad, sometimes ridiculous, but always unexpected. Here are some of the most gasp-inducing moments from the past 12 seasons (yes, 12!). They're still every bit as dramatic, even when you know what's coming.

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    0 of 11

    When Addison Shows Up
    Season 1, Episode 9 (2005)

    Maybe it's just shocking that Seattle Grace's star-crossed lovers have nine relatively happy episodes together before shit starts hitting the fan.

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    1 of 11

    When Cristina Collapses In The OR
    Season 2, Episode 3 (2005)

    Really, what except for a medical emergency could make Dr. Yang miss an answer? A later shock is when Meredith isn't allowed in the OR to hold her hand.

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    2 of 11

    When Izzie Reveals She Has A Daughter
    Season 2, Episode 15 (2006)

    Grey's knows how to handle the big backstory reveals, but this one came from a bit of a misdirect — it seemed safe to assume the biggest secret from Izzie's past had already been exposed: her time as an underwear model.

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    3 of 11

    When Cristina Gets Stabbed By An Icicle
    Season 5, Episode 1 (2008)

    Oh my god, winter is so scary. Nature is scary. Everyone stay inside. But not inside a hospital, though, that's scary too.

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    4 of 11

    When Mark Breaks His Penis
    Season 5, Episode 13

    I mean, in medical terms, he suffers a "penile fracture," but you know that in the years following the incident, when they went out for a drink, Derek and the rest of the Grey's bros referred to it as "that time Mark broke his penis."